FLASHMM - Fast and Scalable Single Cell Differential Expression Analysis using Mixed-Effects Models
A fast and scalable linear mixed-effects model (LMM) estimation algorithm for analysis of single-cell differential expression. The algorithm uses summary-level statistics and requires less computer memory to fit the LMM.
Last updated 2 days ago
5.00 score 2 stars 3 scripts 248 downloadsGWsignif - Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests
The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.
Last updated 9 years ago
1.00 score 1 scripts 188 downloads