R-universe - changjiangxu (Changjiang Xu)

FLASHMM - Fast and Scalable Single Cell Differential Expression Analysis using Mixed-Effects Models

A fast and scalable linear mixed-effects model (LMM) estimation algorithm for analysis of single-cell differential expression. The algorithm uses summary-level statistics and requires less computer memory to fit the LMM.

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5.69 score 11 stars 15 scripts 539 downloads

GWsignif - Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests

The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

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1.00 score 1 scripts 227 downloads